Short review by Prof. Tapani Ruutu opens the issue. It is dedicated to thrombotic angiopathy, a common complication of conditioning therapy in hematopoietic stem cell transplantation (HSCT). Special attention is drawn to erythrocyte schistocytosis as a marker of capillary damage, and its correct diagnostics.

Another review paper by O. V. Galibin et al. concerns natural and synthetic matrices developed for faster and effective regeneration of damaged nerves. Special attention is given to chitosan-containing polymers and biodegradable, electroconductive synthetic carriers allowing to perform regeneration-promoting procedures.

An article by A. B. Chukhlovin deals with some “old” drugs used in a number of non-oncological disorders which may be, in addition, applied for cancer therapy, mostly as a components of combined therapy.

Clinical results of hematopoietic stem cell transplantation from haploidentical donor (e.g., the patients’ parents) are presented in the paper by A. V. Beynarovich et al., addressing mostly clinical outcomes (early and late survival, relapse rates etc. based on a single-center experience.

Prognostic scales in the patients with myelodysplastic syndrome (MDS) show different efficiency, especially when treated with novel therapies. E.V.Morozova et al. compare different prognostic scales in MDS, with respect to appropriate clinical outcomes at long observation terms.

A specialized diagnostics and medical assistance are required in HSCT patients with ORL complications in HSCT patients. These issues are described by E. S. Utimisheva et al. who have focused on sinusitis, its bacterial pathogens, therapeutic effects of maxillary punctures in the patients.

Special clinical case is described by T. A. Bykova et al. who present a description of a patient with a case of familial hemophagocytic lymphohistiocytosis, a rare clinical entity which shows genetic predisposition in some instances.

An experimental study by A. V. Kuznetsov et al. provides original data about mitotic activity and contents of cell in thoracic duct lymph of rabbits, starting from newborns to young adults. Evidence for dividing cells makes it possible to apply these results to the issues of immune recovery in very young mammals including humans, thus being of potential importance in cytostatic therapy.