Volume 2, number 1(5)

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Volume 2, Number 1(5)
05/17/2010

Editor-in-Chief
Afanasyev B. V. (St. Petersburg, Russia)

Co-Editors-in-Chief
Wagemaker G. (Rotterdam, Netherlands)
Zander A. R. (Hamburg, Germany)

Deputy Editor
Chukhlovin A. B. (St. Petersburg, Russia)
Fehse B. (Hamburg, Germany)
Novik A. А. (Moscow, Russia)

Managing Editor
Claudia Koltzenburg (Hamburg, Germany)

Editorial Board
Aleynikova O. (Minsk, Belarus)
Alyansky A. (St. Petersburg, Russia)
Anagnostou A. (Boston, USA)
Andreeff M. (Houston, USA)
Bacher U. (Hamburg, Germany)
Baуkov V. (St. Petersburg, Russia)
Baranov V. S. (St. Petersburg, Russia)
Barkhatov I. (St. Petersburg, Russia)
Baum C. (Hannover, Germany)
Bilko N. (Kiev, Ukraine)
Borset M. (Trondheim, Norway)
Buechner Th. (Muenster, Germany)
Bykov V. (St. Petersburg, Russia)
Dini G. (Genoa, Italy)
Drize N. (Moscow, Russia)
Egeland T. (Oslo, Norway)
Elstner E. (Berlin, Germany)
Emanuel V. (St. Petersburg, Russia)
Everaus H. (Tartu, Estonia)
Ferrara J. (Ann Arbor, USA)
Fibbe W. (Leiden, Netherlands)
Galibin O. (St. Petersburg, Russia)
Ganser A. (Hannover, Germany)
Granov D. (St. Petersburg, Russia)
Ivanov R. (Moscow, Russia)
Klimko N. (St. Petersburg, Russia)
Kolb H.-J. (Muenchen, Germany)
Konopleva M. (Houston, USA)
Koza V. (Pilsen, Czech Republic)
Kroeger N. (Hamburg, Germany)
Malikov A. (St. Petersburg, Russia)
Mikhailova N. (St. Petersburg, Russia)
Mentkevich G. (Moscow, Russia)
Nagler A. (Tel Hashomer, Israel)
Nemkov A. (St. Petersburg, Russia)
Neth R. (Hamburg, Germany)
Nevorotin A.J. (St. Petersburg, Russia)
Ostertag W. (Hamburg, Germany)
Palutke M. (Detroit, USA)
Roumiantsev A. G. (Moscow, Russia)
Savchenko V. G. (Moscow, Russia)
Smirnov A. V. (St. Petersburg, Russia)
Stamm C. (Berlin, Germany)
Tetz V. (St. Petersburg, Russia)
To B. (Adelaide, Australia)
Totolian A. A. (St. Petersburg, Russia)
Uss A.L. (Minsk, Belarus)
Vilesov A. (St. Petersburg, Russia)
Westenfelder Ch. (Salt Lake City, USA)
Wisloff F. (Oslo, Norway)
Zubarovskaya L. (St. Petersburg, Russia)
Zvartau E. (St. Petersburg, Russia)

In this Issue

Abstracts of the joint EBMT Pediatric Working Party – 3rd Raisa Gorbacheva Memorial Meeting, St. Petersburg, Russia, 2009

The aim of the European Group for Blood and Marrow Transplantation (EBMT) is to promote and facilitate access to state-of-the-art and cutting-edge knowledge in blood and marrow transplantation. The EBMT Paediatric Diseases Working Party (EBMT PDWP) has grown during the last few years and currently has more than 20 European countries and at least three non-European countries participating in its activities. This international profile feeds the background against which most of the actual debate on stem cell transplantation in children takes place.

The PDWP firmly believes that children can only be treated by specially trained and experienced pediatric hematopoietic stem cell transplantation (HSCT) teams.

The upcoming meeting will explore the major issues impacting on HSCT in children and adolescents. Leading experts will present and exchange innovative science and discuss specific clinical problems with the audience.

The EBMT PDWP is very enthusiastic about the joint meeting – which will give a full picture of the interdisciplinary approach – and thanks the organizers for the possibility to come to the wonderful venue of St. Petersburg.

Christina Peters
EBMT Chair Paediatric Working Party

Abstracts (Symposium groups)

A. Leukemia treatment
B. Leukemia research
C. Hematopoietic stem cell sources
D. Minimal residual disease
E. Graft-versus-Host Disease
F. Lymphoproliferated diseases (Lymphoma, Myeloma)
G. Complications in hematology (infections, haemostasis abnormalities, fertility)
H. Autoimmune diseases and aplastic anemia
J. Myeloproliferative diseases
K. Inherited diseases
L. Hemoglobinopathies
M. Alternative sources of hematopoietic stem cells (haploidentical relative donors, cord blood)
N. Solid tumors
O. Donor registry

Raisa Gorbacheva Memorial Lecture

Treatment of acute myeloid leukemia: Present status and new directions III
Thomas Büchner

A. Leukemia treatment

Reduced-toxicity conditioning in allogeneic stem cell transplantation for malignant hematological disorders
Tapani Ruutu

Prognostic value of chimerism in patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT)
Maria V. Pryanishnikova, Alexandra A. Sipol, Irina S. Solomonova, Ildar M. Barkhatov, Elena V. Semenova, Liudmila S. Zubarovskaya, Boris V. Afanasyev

Comparing efficacy and toxicity of conditioning regimen “treosulfan+cyclophosphomide” versus “busulfan+cyclophosphomide” in children with hematological malignancies after allogeneic hematopoietic stem cell transplantation
Natalia V. Stancheva, Elena V. Semenova, Natalia I. Zubarovskaya, Yulia G. Vasilieva, Vladimir V. Vavilоv, Irina A. Mushchitskaya, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Survival in adults under 66 years with acute lymphocytic leukemia diagnosed in Norway 2000–2007
Jon-Magnus Tangen¹, Jorg Axel Bohl², Yngvar Floisand³, Einar Haukaas⁴, Inger Anne Naess⁵, Tove Skjelbakken⁶

Thymoglobulin and ATGAM for prevention of posttransplant complications after HLA-mismatched allogeneic SCT
Yury R. Zalyalov, Abdulbasir A. Ganapiev, Boris V. Afanasyev

Epigenetic therapy in childhood AML (pilot study)
Alexander V. Popa¹, Elena S. Gorohova², Elena V. Flejshman³, Larisa G. Fechina⁴, Vladimir V. Lebedev⁵, Karapet S. Aslanyan⁶, Evgenia V. Inyushkina², Svetlana A. Mayakova¹, Irina E. Gavrilova¹, Olga P. Chlebnikova⁴, Elmira G. Boichenko⁷, George L. Mentkevich¹

Efficacy of donor lymphocyte infusions following allogenic stem cell transplantation (allo-HSCT)
Olga A. Slesarchuk, Elena V. Babenko, Maria A. Estrina, Ilya V. Kazantsev, Ludmila S. Zubarovskaya, Boris V. Afanasyev

RIC hematopoietic stem cells transplantation in patients with acute leukemia
Boris V. Afanasyev, Elena V. Semenova

Is it necessary to treat patients after syngeneic bone marrow transplantation?
Lidia S. Lubimova, Larisa A. Kuzmina, Elena N. Parovichnikova, Inna V. Alexeeva, Valeriy G. Savchenko

Results of treatment of relapsed promyelocytic leukemia in children using chemotherapy and arsenic trioxide (ATO) followed by autologous SCT (ASCT)
Dina D. Baidildina, Elena V. Samochatova, Michail A. Maschan, Alexey A. Maschan

Treatment results of childhood acute lymphoblastic leukemia using the COALL-Saint-Petersburg-92 protocol after a 10-year observation period
Elmira G. Boichenko¹, Margarita B. Belogurova², Gritta Janka³, Margarita S. Livshits¹, Eleonora M. Petrova¹, Marina B. Ivanovskaya¹, Irina A. Garbusova¹, Galyna G. Radulesku², Tatjana D. Victorovich², Emylia D. Tchavpetsova², Ludmila I. Shats²

Consequences of ABO incompatibility in allogeneic hematopoietic stem cell transplantation (allo-HSCT)
Maria A. Estrina, Мurat O. Yagmourov, Dmitriy E. Pevtsov, Еvgenia A. Kochina, Natalia E. Ivanova, Alla A. Golovacheva, Alexander L. Alyanskiy, Ludmila S. Zoubarovskaya, Abdulbasir A. Ganapiev, Boris V. Afanasyev

Optimal management of adolescents with acute lymphoblastic leukaemia
Giorgio Dini, Stefano Giardino, Simone Dini

B. Leukemia research

Comparative analysis of acute myeloid leukemia treatment results in the Sverdlovsk Regional Clinical Hospital №1
Alexander V. Vinogradov, Tatiana S. Konstantinova, Alexander F. Tomilov, Vladimir A. Shalaev, Elena V. Chepuryaeva, Julia V. Sveshnikova, Leonid N. Sharov, Natalia V. Vinogradova

Gene therapy of hematopoietic stem cells
Gerard Wagemaker

Determination of FLT3-ITD and D835Y mutations as a factor of prognosis in immunophenotypically verified diagnosis of patients with acute myeloid leukemia in Saint Petersburg
Konstantin U. Slobodnyuk, Irina Y. Saburova, Margarita V. Gorchakova, Ekaterina B. Rusanova, Antonina V. Kurtova, Mikhail I. Zaraiski, Yekaterina E. Zueva

Expression of angiotensin-converting enzymes (ACE, CD143) and shaperons (BiPs, calnexin, calreticulin) by leukemic dendritic cells (LDCs) in acute myeloid leukemia (AML) patients
Irina V. Galtseva¹, Lev M. Pashin¹, Elena N. Parovichnikova¹, Sergei M. Danilov², Andrei B. Sudarikov¹, Ivan A. Vorobiev¹, Valeriy G. Savchenko¹

Posttransplantation leukemia relapses: the role of chromosome changes
Nikolay N. Mamaev, Tatyana L. Gindina, Ildar M. Barkhatov, Boris V. Afanasyev

C. Hematopoietic stem cell sources

Features of a stem cell’s cryopreservation
Alexander B. Smolyaninov, Ksenia V. Korovina, Shirzod F. Adylov, Elena A. Kotelevskaya

Virus markers antibodies detection in umbilical cord blood
Olga V. Supilnikova, Irina I. Maslenikova, Alexander B. Smolyaninov

First experience of CD34+ cell selection to high-risk neuroblastoma patients
Yulia A. Yakovleva^1,2, Grigory A. Tsaur^1,2, Alexander M. Popov^1,2,3, Tatyana Yu. Verzhbitskaya^1,2, Igor N. Vyatkin^1,2, Andrey A. Igumenshev^1,2, Natalya G. Maisheva^1,2, Anton Yu. Zadoya^1,2, Egor V. Shorikov^1,2, Leonid I. Savelyev^1,2,3, Larisa G. Fechina^1,2

Effectiveness of hematopoietic progenitor cell separation with the help of the Sepax S100 cell separator
Alexander B. Smolyaninov, Dmitry A. Ivolgin, Shirzod F. Adylov, Elena A. Kotelevskaya

Low and high-resolution HLA typing of cord blood samples of register of donors in St. Petersburg
Elena A. Kotelevskaya, Svetlana A. Smirnova, Alexander B. Smolyaninov

Importance of CFU-GM number for prediction of hematological reconstitution after low CD34+ cell dose autotransplantation in children
Yanina I. Isaikina, Valery I. Martinevsky, Nina V. Minakovskaya, Yury S. Strongin, Olga V. Aleinikova

Selection of optimal cryopreservation strategy for hematopoietic stem cells
Leonid I. Savelyev^1,2,3, Yulia A. Yakovleva¹, Grigory A. Tsaur^1,2, Tatyana Yu. Verzbitskaya^1,2, Alexander M. Popov^1,2,3, Andrey A. Igumenshev^1,2, Larisa V. Vakhonina^1,2, Igor N. Vyatkin^1,2, Egor V. Shorikov^1,2, Larisa G. Fechina^1,2

Is young matched unrelated donor comparable or superior to older sibling donor? An analysis of 76 allografted patients aged above 50 years from the Czech Acute Leukaemia Clinical Register (ALERT)
Vladimir Koza¹, Pavel Jindra¹, Karel Indrak², Fedor Alsabty³, Sarka Hrabetova⁴

D. Minimal residual disease

Algorithm for monitoring minimal residual disease on the basis of patient-associated immunophenotypes
Yekaterina E. Zueva, Margarita V. Gorchakova, Ekaterina B. Rusanova, Konstantin U. Slobodnyuk

Slow fusion gene transcript clearance predicts poor outcome in infants with MLL-rearranged acute lymphoblastic leukemia
Grigory A. Tsaur^1,2, Tatyana V. Nasedkina³, Alexander M. Popov^1,2,4, Anna S. Ivanova^1,2, Yulia A. Yakovleva^1,2, Tatyana O. Riger^1,2, Egor V. Shorikov^1,2, Leonid I. Saveliev^1,2,4, Larisa G. Fechina^1,2

Detection of minimal residual disease (MRD) by flow cytometry in children with acute lymphoblastic leukemia (ALL)
Margarita G. Bozhieva, Ludmila Y. Grivtsova, Alexander V. Popa, Irina N. Serebryakova, Irina E. Gavrilova, Boris V. Kurdyukov, Rono S. Ravshanova, Georgiy L. Mentkevich, Nikolay N. Tupitsyn

Comparison of MRD data assessed by flow cytometry and RT-PCR of fusion gene transcripts in infants with MLL-rearranged ALL
Alexander M. Popov^1,2,3, Grigory A. Tsaur^1,2, Anna S. Ivanova^1,2, Yulia A. Yakovleva^1,2, Tatiana Y. Verzhbitskaya^1,2, Tatiana O. Riger¹, Egor V. Shorikov^1,2, Leonid I. Savelyev^1,2,3, Larisa G. Fechina^1,2

E. Graft-versus-Host Disease

The comparative characteristic toxicity and immunosuppressive activity both tacrolimus and cyclosporine in patients undergoing allo-HSCT
Yulia A. Stankevich, Ludmila S. Zubarovskaya, Elena V. Semenova, Sergey M. Alexeev, Elena V. Babenko, Boris V. Afanasyev

Eye graft-versus-host disease in patients with allogeneic hematopoietic stem cell transplantation (updated data)
Alexandra L. Mikhaylova¹, Yuri S. Astakhov², Boris V. Afanasyev¹

Applying mesenchymal stem cells for the prevention and treatment of steroid-resistant GVHD in children in Belarus
Nina V. Minakovskaya, Yanina I. Isaikina, Olga V. Aleinikova

Spirometry findings in bone marrow transplant patients
Larisa A. Kuzmina, Lidia S. Lubimova, Valeriy G. Savchenko

Chronic graft-versus-host disease in children and adolescents
Anita Lawitschka

Evidence of the “graft-versus-tumor” effect following haploidentical transplantation in a patient with a metastatic relapse of Ewing’s sarcoma
Igor S. Dolgopolov, Roman I. Pimenov, Vasilii K. Boyarshinov, Natalia S. Subbotina, George L. Mentkevich

F. Lymphoproliferated diseases (Lymphoma, Myeloma)

Prognostic value of apoptosis of tumor clone bone marrow cells in patients with multiple myeloma
Zhanna V. Chubukina, Ludmila N. Bubnova, Stanislav S. Bessmeltsev

Expression of tumor-associated genes in multiple myeloma patients during high-dose chemotherapy and auto-SCT
Tatiana V. Gaponova, Lidia S. Mendeleeva, Andrey V. Misurin, Elena Yu. Varlamova, Elena N. Parovichnikova,
Valeriy G. Savchenko

Supporting therapy of natural zeolites at patients with lymphoproliferative diseases
Anna S. Chernyshova, Lev E. Panin

Treatment results of children with Hodgkin’s disease (HD) according to protocols DAL-HD and GPOH-HD
Margarita B. Belogurova^1,2, Galina G. Radulesku^1,2, Tatyana D. Viktorovich^1,2, Emilia D. Chavpetsova², Ludmila I. Shats^1,2, Yulia V. Dinikina¹

Cellular factors of antitumor immunity in patients with chronic lympholeukemia
Natalya V. Issayeva, Galina A. Zaitseva, Tamara P. Zagoskina

Salvage therapy in relapsed Hodgkin's lymphoma patients
Elena S. Belyaeva, Olga V. Morozova, Andrey I. Slugin, Alexander V. Popa, Georgy L. Mentkevich

Clinical and pathological characterization of the t(14;19)(q32;q13)-positive splenic marginal zone lymphoma
Hunan L. Julhakyan, Tatyana N. Obukhova, Irina B. Kaplanskaya, Rima S. Samoylova, Andrey I. Vorobiev

Effects of targeted therapy of multiple myeloma according to the City Hematological Center of Novosibirsk
Natalia V. Skvortsova, Tatiana I. Pospelova, Sofia J. Kovalchuk

Association between HLA class I antigens and survival length in patients with multiple myeloma
Elena A. Senkina, Galina A. Zaitseva, Tamara P. Zagoskina, Konstantin A. Martynov

High-dose melphalan versus melphalan plus dexamethasone in patients with AL amyloidosis
Anna G. Smirnova¹, Alexey V. Smirnov², Axel R. Zander³, Boris V. Afanasyev¹

The role of p53 polymorphisms in non–Hodgkin’s lymphomas’ susceptibility and prognosis
Elena N. Voropaeva, Tatiana I. Pospelova, Mikhail I. Voevoda, Olga V. Beresina

Virus participation in renal damage in AL patients: histopathological study
Ekaterina G. Vorozheikina¹, Vladimir V. Varshavski², Ekaterina P. Golitsina², Evgenia N. Glasko¹, Irina B. Kaplanskaya¹, Ljudmila S. Birjukova¹, Elena N. Parovichnikova¹, Valeriy G. Savchenko¹

Bone marrow angiogenesis is a prognostic value in patients with multiple myeloma undergoing high-dose therapy and autologous stem cell transplantation
Olga S. Pokrovskaya, Lidia S. Mendeleeva, Irina B. Kaplanskaya, Elena Yu. Varlamova, Elena N. Parovichnikova, Sergey M. Kulikov, Valeriy G. Savchenko

Allogeneic stem cell transplantation in multiple myeloma: single centre experience of 112 patients
Liisa Volin, Heli Uotinen, Eeva Juvonen, Anne Nihtinen, Tapani Ruutu

Unusual B-cell lymphoproliferative disorders and the new WHO classification
Margarita Palutke

Cases of secondary acute myeloid leukemia and myelodysplastic syndrome in patients with multiple myeloma
Alexander S. Luchinin

Anemias in lymphomas: pathogenesis mechanisms
Anna S. Lyamkina, Tatiana I. Pospelova

Genetic polymorphisms of CYP1A1, GSTM1, GSTT1, and GSTP1 genes in В-cellular chronic lymphocytic leukemia (B-CLL)
Vanik A. Ovsepyan, Vitaliy A. Rosin

Impact of positron emission tomography on primary staging and changing the therapeutic modality in lymphoma patients
Natalia B. Mikhaylova¹, Marina S. Tlostanova², Yulia N. Vinogradova², Ekaterina I. Ivanova², Anna V. Kritskaya², Sergey E. Korolev¹, Anna A. Rats¹, Alexander A. Pugachev¹, Nikolay V. Ilyin², Boris V. Afanasyev¹, Leonid A. Tyutin²

G. Complications in hematology (infections, haemostasis abnormalities, fertility)

Epidemiology of bacterial infections and antibiotic resistance in BMT clinic: single center experience
Vladimir N. Vavilov¹, Olga B. Ponomarenko¹, Marina O. Popova¹, Svetlana S. Emelyanova², Maria Yu. Averjanova¹, Oleg V. Goloschapov¹, Ludmila S. Zubarovskaya¹, Boris V. Afanasyev¹

Management of resistant or recurrent CMV infection following allogeneic SCT
Petr Sedlacek¹, Ladislav Krol¹, Petr Hubacek¹, David Boutolleau², Tomas Kalina¹

C-reactive protein (CRP) concentration in patients with acute myeloblastic leukemia (AML) manifestation
Sofia G. Vladimirova, Lyudmila N. Tarassova, Gulzada N. Mustafina, Valentina V. Cherepanova

Invasive fungal disease (IFD) in patients after allogeneic hematopoietic stem cell transplantation: single center experience
Natalia I. Zubarovskaya¹, Yulia G. Vasilieva¹, Natalia V. Stancheva¹, Elena V. Semenova¹, Vladimir N. Vavilov¹, Svetlana Emelyanova², Nikolay N. Klimko³, Boris V. Afanasyev¹

Hemostasis in patients with acute myeloblastic leukemia (AML) manifestation
Valentina V. Cherepanova, Sofia G. Vladimirova, Lyudmila N. Tarassova, Gulzada N. Mustafina, Natalia N. Silina

Correlations between reactivation of herpesviruses and common complications of allo-HSCT
Olga S. Pankratova, Alexey B. Chukhlovin, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Risk factors of invasive candidiasis in children with leukemia
Elmira G. Boichenko, Alexey S. Kolbin

H. Autoimmune diseases and aplastic anemia

Mesenchymal stem cell transplantation in patents with amyotrophic lateral sclerosis and multiple sclerosis
Miroslav M. Odinak¹, Gennadiy N. Bisaga¹, Andrey V. Novitsky², Vadim V. Tirenko², Dmitriy N. Sculyabin¹, Dmitriy G. Polyntsev³, Petr V. Krugliakov³, Anna N. Bilibina³, A. Kolchenko³

Outcomes of hematopoietic cell transplantation (SCT) and combined immunosupression (IST) patients with severe aplastic anemia (SAA) admitted with life-threatening infections
Galina A. Novichkova, Mikhail A. Maschan, Lili A. Khachatrian, Dina D. Baidildina, Olga V. Goronkova, Galina G. Solopova, Elena V. Skorobogatova, Irina P. Shipitsina, Alexey A. Maschan

Alternative method for treating acquired aplastic anemia
Yuri I. Yugov, Nina A. Fedorovskaya, Alexander S. Luchinin

The severity of acquired aplastic anemia (AA) and long-term prognosis: lessons from current results of immunosuppressive treatment (IST)
Alexander D. Kulagin^1,2, Igor A. Lisukov^1,2, Vyacheslav I. Borisov², Irina V. Kruchkova², Vera V. Sergeevicheva², Svetlana A. Sizikova², Andrey V. Gilevich², Vladimir S. Kozhevnikov², Vladimir A. Kozlov²

Immunoablation followed by autologous stem cell transplantation in refractory autoimmune diseases: clinical outcomes and immune reconstitution
Igor A. Lisukov^1,2, Vera V. Sergeevicheva², Svetlana A. Sizikova², Alexander D. Kulagin^1,2, Irina V. Kruchkova², Andrey V. Gilevich², Alexey E. Sizikov², Lyudmila P. Konenkova², Elena R. Chernykh², Vladimir S. Kozhevnikov², Alexander A. Demin¹, Vladimir A. Kozlov²

J. Myeloproliferative diseases

Decitabine for treatment of relapsed myelodysplastic syndrome after allogeneic stem cell transplantation: Case report
Yulia V. Rudnitskaya, Elena V. Morozova, Boris V. Afanasyev

Index granularity of neutrophils in peripheral blood as a new application for screening myelodysplastic syndromes using flow cytometry
Ekaterina B. Rusanova¹, Konstantin U. Slobodnyuk¹, Margarita V.Gorchakova¹, Yekaterina E. Zueva¹, Ramon Simon-Lopez²

Case report: combined myeloid and lymphoid lineage disorders in patient with chronic eosinophilic leukemia and T-cell lymphoma
Margarita V. Gorchakova, Ekaterina B. Rusanova, Konstantin U. Slobodnyuk, Irina J. Saburova, Elena A. Stadnik, Michail I. Zaraiski, Yekaterina E. Zueva

K. Inherited diseases

Hematopoietic stem cell transplantation (HSCT) in patients with severe combined immunodeficiency (SCID): experiences, possibilities, and prospects
Dmitry N. Balashov, Pavel E. Trakhtman, Elena V. Skorobogatova, Yulia V. Skvortsova, Zarema M. Dyshlevaja, Irina P. Shipitsina, Alexey A. Maschan, Alexander G. Rumyantsev

L. Hemoglobinopathies

Outcomes after addition of rabbit-ATG to the standard Bu+CY preparative regimen for allogeneic matched sibling donor (MSD) hematopoietic stem cell transplantation (HSCT) for hemoglobinopathies in children: a single center experience
Sandeep Soni, MD¹, Micah Skeens, RN, MSN¹, Thomas E. Gross, MD¹, Rajinder P. Bajwa, MD¹, Kathryn Klopfenstein, MD²,
K. Scott Baker, MD, MS³, Amanda M.Termuhlen, MD¹

M. Alternative sources of hematopoietic stem cells (haploidentical relative donors, cord blood)

Haploidentical SCT as a salvage therapy in hematological malignancies: A single center experience
Olesya V. Paina, Yulia A. Stankevich, Ilya V. Kazantsev, Natalia V. Stancheva, Alla A. Golovacheva, Elena V. Babenko, Alexander L. Alyanskiy, Natalia E. Ivanova, Elena V. Semenova, Petr V. Krugliakov, Dmitriy G. Polyntsev, Liudmila S. Zubarovskaya, Boris V. Afanasyev

Non-T-cell depleted haploidentical HSCT after RIC in pediatric malignancies
Natalia S. Subbotina, Igor S. Dolgopolov, Roman I. Pimenov, Vasilii K. Boyarshinov, George L. Mentkevich

Properties of cord blood stem cells chromatin
Vladimir S. Tolmachev, Elizaveta I. Borovitskaya, Natalia O. Kudrina, Tatiana G. Kravtsova

Ex vivo expanded hematopoietic progenitor cells (HPC) from cord blood in clinical trials for patients with hematological malignancies
Yael Margolin, David Snyder, Tony Peled

Prognostic factors in cord blood stem cell quality
Artur A. Isaev, Alexander V. Prihodko, Sergey L. Kiselev, Maria A. Lagarkova, Ivan V. Potapov, Alexey V. Lundup

Developing new immunological compatible transplants derived from umbilical cord
Artur A. Isaev¹, Alexander V. Prihodko¹, Irina N. Saburina², Sergey L. Kiselev¹, Varvara S. Melihova², Ivan V. Potapov¹, Alexey V. Lundup¹

N. Solid tumors

Aggressiveness of tumor resection improves survival in pediatric malignant gliomas
Ludmila I. Shats¹, Margarita B. Belogurova¹, Olga G. Zheludkova²

First experience of treatment of high-risk neuroblastoma patients using autologous peripheral blood stem cells transplantation
Igor N. Vyatkin^1,2, Egor V. Shorikov^1,2, Andrey A. Igumenshev^1,2, Larisa V. Vakhonina^1,2, Natalya G. Maisheva^1,2, Yulia A. Yakovleva^1,2, Grigory A. Tsaur^1,2, Alexander M. Popov^1,2,3, Elizaveta R. Semenikhina¹, Leonid I. Savelyev^1,2,3, Larisa G. Fechina^1,2

Treatment of patients with high-risk axial and pelvic Ewing’s sarcoma (ES). A single-institution experience
Roman I. Pimenov¹, Igor S. Dolgopolov¹, Vasilii K. Boyarshinov¹, Natalia S. Subbotina¹, Igor V. Visochin¹, Stuart Siegiel², George L. Mentkevich¹

High-dose chemotherapy and autologous stem cell transplantation in children with Ewing’s sarcoma/PNET
Ilya V. Kazantsev¹, Tatjana V. Youhta², Elena V. Morozova¹, Svetlana A. Safonova², Yury A. Punanov², Liudmila S. Zubarovskaya¹, Boris V. Afanasyev¹

Restoration of ovarian function after cryopreserved ovarian tissue transplantation in women exposed to complex treatment for gynecological cancer: feasibility of this option in pediatric cancer patients
Alla S. Lisyanskya^1,2, Natalia I. Tapilskaya^1,3, Margarita B. Belogurova^3,4, Yulia V. Dinikina³, Ekaterina V. Tsibatova⁴, Georgy M. Manikhas¹

The outcome of treatment in patients with high-risk (HR) retinoblastoma
Igor S. Dolgopolov¹, Tatiana L. Ushakova¹, Olga N. Gorovtzova¹, Alevtina I. Pavlovskaya², Roman I. Pimenov¹, Vasilii K. Boyarshinov¹, Natalia S. Subbotina¹, Igor V. Glekov¹, Vladimir G. Poliakov¹, George L. Mentkevich¹

O. Donor registry

Influence of differentiated occurrence of HLA genes and haplotypes on defined clinical parameters in patients after allo–HSCT in association with HLA polymorphism
Alexander L. Alyanskiy, Olesya V. Paina, Natalia E. Ivanova, Alla A. Golovacheva, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Cellular Therapy and Transplantation, 2015

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