Cellular Therapy and Transplantation

Cellular Therapy and Transplantation is an international, peer-reviewed, Open Access journal which publishes articles in the fields of cellular and gene therapy and tissue transplantation. We welcome original research articles, review articles, short communications and clinical case reports. The major criteria for acceptance and publication of a manuscript are originality, high quality, scientific rigor, and interest to a wide audience of readers. The journal is issued in printed and digital version (www.cttjournal.com)

Editorial work, processing and publication of the articles are free of charge for the authors.

Papers accepted for publication in CTT are made available on this site at no charge to readers (Open Access). The articles published in CTT are provided under the following license: Creative Commons Attribution 3.0 Unported, http://creativecommons.org/licenses/by/3.0/ Authors retain the copyright of their contributions.

Volume 10, Number 3
09/30/2021

Editor-in-Chief
Kulagin A. D. (St. Petersburg, Russia)

Co-Editors-in-Chief
Wagemaker G. (Rotterdam, Netherlands)
Zander A. R. (Hamburg, Germany)

Deputy Editor
Fehse B. (Hamburg, Germany)

Managing Editor
Chukhlovin A. B. (St. Petersburg, Russia)

Editorial Board
Aleynikova O. V. (Minsk, Belarus)
Borset M. (Trondheim, Norway)
Chechetkin A. V. (St. Petersburg, Russia)
Fibbe W. (Leiden, Netherlands)
Gale R. P. (Los Angeles, USA)
Galibin O. V. (St. Petersburg, Russia)
Hehlmann R. (Mannheim, Germany)
Hölzer D. (Frankfurt a.M., Germany)
Klimko N. N. (St. Petersburg, Russia)
Kolb H.-J. (München, Germany)
Kröger N. (Hamburg, Germany)
Lange C. (Hamburg, Germany)
Mamaev N. N. (St. Petersburg, Russia)
Mikhailova N. B. (St. Petersburg, Russia)
Moiseev I. S. (St. Petersburg, Russia)
Nagler A. (Tel-Aviv, Israel)
Nemkov A. S. (St. Petersburg, Russia)
Paramonov I. V. (Kirov, Russia)
Roumiantsev A. G. (Moscow, Russia)
Savchenko V. G. (Moscow, Russia)
Smirnov A. V. (St. Petersburg, Russia)
Uss A. L. (Minsk, Belarus)
Zubarovskaya L. S. (St. Petersburg, Russia)

In this Issue

Editorial

XV Raisa Gorbacheva Memorial Meeting Hematopoietic Stem Cell Transplantation. Gene and Cellular Therapy: An overview

Alexander D. Kulagin, Editor-in-Chief, Cellular Therapy and Transplantation, Alexey B. Chukhlovin

Award Session: AW-01 – AW-03

AW-01. The results of a retrospective multicenter study: epidemiology of HIV-related Non-Hodgkin lympoma

Аndrey М. Chekalov¹, Marina О. Popova¹, Ivan V. Tsygankov¹, Yulia А. Rogacheva¹, Nikita P. Volkov¹, Anastasia V. Beynarovich¹, Kirill V. Lepik¹, Мarina V. Demchenkova², М. V. Grigorieva², Тatyana V. Schneider³, Yulia V. Kopeikina³, Vsevolod G. Potapenko⁴, Nadezhda V. Medvedeva⁴, Ilya S. Zyuzgin⁵, Мaria А. Kolesnikova⁶, Тatyana I. Pospelova⁶, Еlena Е. Zinina⁷, Аlexander А. Myasnikov⁸, Кamil D. Kaplanov⁹, Тatyana I. Ksenzova¹⁰, Stella S. Zola¹¹, Еlena S. Pavlyuchenko¹², Natalya B. Mikhailova¹, Vadim V. Baykov¹, Аlexander D. Kulagin¹

AW-02. Chimerism in the population of T-regulatory cells as a predictive marker for late acute graft-versus-host disease development in patients with acute leukemia after allogeneic hematopoietic stem cells transplantation

Darya S. Dubnyak, Natalya V. Risinskaya, Mikhail Y. Drokov, Vera A. Vasilyeva, Olga S. Starikova, Ulyana V. Maslikova, Ekaterina D. Mikhaltsova, Natalia N. Popova, Anna A. Dmitrova, Olga M. Koroleva, Natalia M. Nikiforova, Zoya V. Konova, Mobil I. Akhmedov, Mariya V. Dovydenko, Feruza A. Omarova, Elmira I. Kolgaeva, Julia O. Davydova, Nikolay М. Kapranov, Larisa A. Kuzmina, Irina V. Galtseva, Andrey B. Sudarikov, Elena N.Parovichnikova

AW-03. Treatment strategy for the patients with relapsed and refractory classical Hodgkin lymphoma after PD-1 inhibitors failure: experience at the Pavlov University

Liudmila V. Fedorova, Kirill V. Lepik, Elena V. Kondakova, Evgenia S. Borzenkova, Anastasia V. Beynarovich, Polina V. Kotselyabina, Marina O. Popova, Ivan S. Moiseev, Natalia B. Mikhailova, Alexander D. Kulagin

Acute leukemias: AL-01 – AL-06

AL-01. Factors of relapse-free survival in the context of prophylactic tyrosine kinase inhibitors administration after allogeneic hematopoietic stem cell transplantation in adults with Ph-positive acute lymphoblastic leukemia

Kseniia S. Afanaseva, Evgeny A. Bakin, Olga V. Pirogova, Anna G. Smirnova, Ildar M. Barkhatov, Tatiana L. Gindina, Ivan S. Moiseev, Sergey N. Bondarenko, Alexander D. Kulagin

AL-02. Treatment options for the patients over 18 years old with refractory/relapsing acute myeloid leukemia

Bella I. Ayubova¹, Sergey N. Bondarenko¹, Ivan S. Moiseev¹, Anna G. Smirnova¹, Olga S. Uspenskaya², Elena V. Karyagina³, Evgenia I. Zhelnova⁴, Elena V. Babenko¹, Ildar M. Barkhatov¹, Tatyana L. Gindina¹, Alexander D. Kulagin¹

AL-03. Gilteritinib in relapsed or refractory acute myeloid leukemia FLT3+ in adult patients

Sergey N. Bondarenko¹, Elena V. Morozova¹, Anna G. Smirnova¹, Yulia Yu. Vlasova¹, Bella I. Ayubova¹, Elena V. Karyagina², Ridvan K. Ilyasov³, Natalya A. Zorina⁴, Svetlana S. Belyaeva⁵, Yulia S. Neredko⁶, Irina A. Samorodova⁷, Yulia B. Chernih⁸, Mikhail Yu. Lazarev⁹, Anna P. Kochergina¹⁰, Nikolai Yu. Tcvetkov¹, Mikhail M. Kanunnikov¹, Yulia D. Oleynikova¹, Dmitry K. Zhogolev¹, Ildar M. Barkhatov¹, Tatiana L. Gindina¹, Ivan S. Moiseev¹, Alexander D. Kulagin¹

AL-04. Cytogenetic analysis of complex chromosome aberrations in the patients with acute myeloid leukemia using multicolour fluorescent in situ hybridization

Tatiana Yu. Gracheva, Maria V. Latypova, Anastasia A. Khabibullina, Irina A. Petrova, Diana S. Ilyasova, Elena S. Ryabikova, Tatiana L. Gindina

AL-05. Haploidentical hematopoietic stem cell transplantation for chemoresistant relapses of acute leukemia in children

Dair Nurgaliev, Balzhan Umirbekova, Gulshat Kusherova

AL-06. Impact of pre allo-HSCT MRD status on relapse prophylaxis in high-risk acute myeloid leukemia in children

Zhemal Z. Rakhmanova, Svetlana V. Razumova, Olesya V. Paina, Polina V. Kozhokar, Anastasia S. Frolova, Liubov A. Tsvetkova, Elena V. Babenko, Tatyana L. Gindina, Alexandr L. Alyanskiy, Ildar M. Barkhatov, Elena V. Semenova, Ludmila S. Zubarovskaya

Lymphomas: LY-01 – LY-08

LY-01. Clinical outcomes of allogeneic hematopoietic stem cell transplantation in classical Hodgkin lymphoma

Anastasia V. Beynarovich, Kirill V. Lepik, Natalia B. Mikhailova, Evgenia S. Borzenkova, Nikita P. Volkov, Elena V. Kondakova, Lilia V. Stelmakh, Elena V. Babenko, Ivan S. Moiseev, Alexander D. Kulagin

LY-02. Upfront allogeneic HSCT in a patient with plasmablastic lymphoma with TP53 mutation

Nelly G. Gabeeva, Daria A. Koroleva, Mikhail Yu. Drokov, Bella V. Biderman, Svetlana A. Tatarnikova, Alla M. Kovrigina, Tatiana N. Obukhova, Larisa A. Kuzmina, Evgeny E. Zvonkov, Elena N. Parovichnikova

LY-03. Treatment of mantle cell lymphoma: experience of the RM Gorbacheva Research Institute

Polina V. Kotselyabina, Liudmila V. Fedorova, Kirill V. Lepik, Elena V. Kondakova, Yuri R. Zalyalov, Evgenia S. Borzenkova, Nikita P. Volkov, Ivan S. Moiseev, Natalia B. Mikhailova, Alexander D. Kulagin

LY-04. Autologous hematopoietic stem cell transplantation in children with primary mediastinal large B-cell lymphoma

Andrey V. Kozlov, Ilya V. Kazantsev, Tatiana V. Iukhta, Polina S. Tolkunova, Asmik G. Gevorgian, Ilya Y. Nikolaev, Alexander N. Galimov, Olga I. Bogdanova, Daria A. Zvyagintseva, Margarita S. Golenkova, Olesia S. Yudintseva, Alexander N. Shvetsov, Vadim V. Baykov, Elena V. Babenko, Maria A. Estrina, Yuri A. Punanov, Elena V. Morozova, Alexander D. Kulagin, Natalia B. Mikhailova, Ludmila S. Zubarovskaya

LY-05. Role of hematopoietic stem cell transplantation in the treatment of peripheral T-cell lymphomas: a multicenter experience

Elena E. Lepik¹, Vladislav V. Kovalik¹, Andrey V. Kozlov¹, Evgenia S. Borzenkova¹, Kirill V. Lepik¹, Elena V. Kondakova¹, Vadim V. Baykov¹, Ivan S. Moiseev¹, Tatiana V. Shneider², Olga S. Uspenskaya², Marina V. Demchenkova³, Vera V. Sergeevicheva⁴, Vadim M. Kemaikin⁵, Natalia B. Mikhailova¹, Alexander D. Kulagin¹

LY-06. Dual resistance to bortezomib and lenalidomide frequency in patients with multiple myeloma. A single center experience

Vsevolod G. Potapenko, Roman V. Vashchenkov, Natalia V. Dorofeeva, Elmira N. Dulaeva, Julia V. Zabutova, Anna V. Klimovich, Natalia A. Kotova, Maria I. Nabilkova, Olga V. Nebelitskaya, Victoria V. Ryabchikova, Irina A. Samorodova, Alexander V. Serkov, Irina A. Skorokhod, Ksenia А. Skoryukova, Daria A. Chaginskaya, Nadezhda V. Medvedeva

LY-07. Polatuzumab vedotin in combination with bendamustine and rituximab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: interim analysis of real life experience CIC 725

Olesya G. Smykova, Vladislav V. Markelov, Liudmila V. Fedorova, Kirill V. Lepik, Elena V. Kondakova, LiliaV. Stelmakh, Ivan S. Moiseev, Natalya B. Mikhailova, Alexander D. Kulagin

LY-08. Treatment of large plasmacytoma in patients with multiple myeloma (clinical case)

Maryna A. Tsiarentsyeva, Ihar A. Iskrou, Aleh N. Kozak, Dzmitryj E. Trachanou

Chronic hematological malignancies: CM-01 – CM-07

CM-01. Glomerular filtration rate and the chronic lymphocytic leukemia patients survival

Maria V. Markovtseva¹, Ekaterina N. Zguralskaya²

CM-02. Results of allogeneic hematopoietic stem cell transplantation in children and adolescents with high-risk myelodysplastic syndrome

Anna A. Osipova, Tatyana A. Bykova, Varvara N. Ovechkina, Anastasia S. Borovkova, Olesya V. Paina, Polina V. Kozhokar, Kirill A. Ekushov, Svetlana V. Razumova, Alexander L. Alyanskiy, Elena V. Morozova, Elena V. Babenko, Tatyana L. Gindina, Elena V. Semenova, Alexander D. Kulagin, Ludmila S. Zubarovskaya

CM-03. Regulation of TIM-3 expression in myeloid neoplasms

Anna N. Parfenenkova, Ildar M. Barkhatov, Olga S. Epifanovskaya, Alena I. Shakirova, Nikolai Yu. Tcvetkov, Elena V. Babenko, Kirill V. Lepik, Elena V. Morozova, Ivan S. Moiseev

CM-04. Possibilities of cytogenetic analysis of blood cells in the diagnosis of myelofibrosis

Irina A. Petrova, Maria V. Latypova, Tatiana Y. Gracheva, Anastasia A. Khabibullina, Diana S. Ilyasova, Maria E. Vlasova, Tatiana L. Gindina

CM-05. Surgical management of a histiocytic tumor of unknown malignancy potential: Case report

Vsevolod G. Potapenko¹, Yurij A. Krivolapov², Elena E. Leenman², Jean-François Emile³

CM-06. Timing of allogeneic hematopoietic stem cell transplantation in patients with high risk myelodysplastic syndrome

Nikolai Yu. Tcvetkov, Ivan S. Moiseev, Maria V. Barabanshikova, Kseniia S. Iurovskaia, Zarema K. Abdulkhalikova, Yulia Yu. Vlasova, Alexander D. Kulagin, Elena V. Morozova

CM-07. Prognostically unfavorable immunophenotypic and cytogenetic markers of transformation into acute leukemia in adult patients with myelodysplastic syndrome

Hanna S. Trubkina, Ihar A. Iskrou, Irina Yu. Lendina, Victoria V. Smolnikova, Tatiana V. Lebedeva

Aplastic anemia and cytopenias: AA-01 – AA-02

AA-01. COVID-19 in patients with bone marrow failure and paroxysmal nocturnal hemoglobinuria

Darya A. Chebykina, Irina K. Golubovskaya, Yuriy N. Kuznetsov, Maria V. Bogomolova

AA-02. Influence of KIR2DL3 positivity on graft failure development after allogeneic hematopoietic stem cells transplantation

Ulyana V. Maslikova, Mikhail Yu. Drokov, Ekaterina D. Mikhaltsova, Olga S. Starikova, Maria V. Dovydenko, Olga M. Koroleva, Daria S. Dubnyak, Natalia N. Popova, Anna A. Dmitrova, Zoya V. Konova, Igor Yu. Urybin, Vera A. Vasilyeva, Larisa A. Kuzmina, Ekaterina G. Khamaganova, Elena N. Parovichnikova, Valery G. Savchenko

Immune complications: IC-01 – IC-06

IC-01. Post-transplant сyclophosphamide versus conventional GVHD prophylaxis in unrelated donor hematopoietic stem cell transplantation in children with acute myeloid leukemia

Anastasia S. Borovkova, Olesia V. Paina, Zhemal Z. Rakhmanova, Polina V. Kozhokar, Anastasiia S. Frolova, Lubov A. Tsvetkova, Svetlana V. Razumova, Kirill A. Ekushov, Inna V. Markova, Anna A. Osipova, Tatiana A. Bykova, Elena V. Babenko, Alexandr L. Alyanskiy, Ildar M. Barkhatov, Elena V. Semenova, Alexander D. Kulagin, Ivan S. Moiseev, Ludmila L. Zubarovskaya

IC-02. Dynamics of cellular immunity in patients with acute myeloid and acute lymphoblastic leukemia at the stage of induction therapy as an indicator of secondary immunodeficiency

Olga V. Gerasimovich, Ihar A. Iskrou, Irina Yu. Lendina

IC-03. Portable non-invasive lung ventilation for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation

Anna A. Obukhova¹, Victoria A. Pavlova¹, Nikita V. Markov¹, Arina V. Zinchenko¹, Christina A. Popova², Yuriy N. Kuznetsov³, Valeria R. Yanbukhtina³, Egor A. Kulagin⁴, Ruth D. Skvortsova^1,5, Julia D. Rabik^2,5, Anna G. Smirnova³, Alexander N. Kulikov⁵

IC-04. Influence of HLA donor-recipient compatibility on T-cell immunity restoration in patients after allogeneic stem cell transplantation

Feruza A. Omarova, Natalia N. Popova, Julia O. Davydova, Nikolay M. Kapranov, Mikhail Yu. Drokov, Olga S. Starikova, Ulyana V. Maslikova, Zoya V. Konova, Elmira I. Kolgaeva, Ekaterina D. Mikhaltsova, Mariya V. Dovydenko, Olga M. Koroleva, Anna A. Dmitrova, Darya S. Dubnyak, Mobil I. Akhmedov, Anna S. Garmash, Ksenia A. Nikiforova, Vera A. Vasilyeva, Larisa A. Kuzmina, Irina V. Galtseva, Elena N. Parovichnikova

IC-05. The role of CD8+ T naive and memory stem cells in acute GVHD development after allogeneic hematopoietic stem cell transplantation performed in patients with acute leukemia

Natalia N. Popova, Mikhail Yu. Drokov, Julia O. Davydova, Nikolay М. Kapranov, Feruza A. Omarova, Ulyana V. Maslikova, Ekaterina D. Mikhaltsova, Olga M. Koroleva, Zoya V. Konova, Anna A. Dmitrova, Mariya V. Dovydenko, Olga S. Starikova, Darya S. Dubnyak, Elmira I. Kolgaeva, Natalia M. Nikiforova, Vera A. Vasilyeva, Irina V. Galtseva, Larisa A. Kuzmina, Elena N. Parovichnikova

IC-06. Impact of lung involvement on overall survival in chronic GVHD patients

Vera A. Vasilyeva, Larisa A. Kuzmina, Mikhail Yu. Drokov, Mariya V. Dovydenko, Olga M. Koroleva, Olga S. Starikova, Darya S. Dubnyak, Anna A. Dmitrova, Natalya M. Nikiforova, Ekaterina D. Mikhaltsova, Natalya N. Popova, Zoya V. Konova, Mobil I. Akhmedov, Ulyana V. Maslikova, Elena N. Parovichnikova, Valery G. Savchenko

Posttransplant infections: PI-01 – PI-06

PI-01. Risk factors for bloodstream infections after first allogeneic hematopoietic stem cell transplantation

Mobil I. Akhmedov, Galina A. Klyasova, Elena N. Parovichnikova, Larisa A. Kuzmina, Vera A. Vasilyeva, Mikhail Yu. Drokov, Mariya V. Dovydenko, Anastasia V. Fedorova, Natalia N. Popova, Zoya V. Konova, Feruza A. Omarova, Olga S. Starikova, Ulyana V. Maslikova, Ekaterina D. Mikhaltsova, Olga M. Koroleva, Anna A. Dmitrova, Darya S. Dubnyak, Valery G. Savchenko

PI-02. Treatment of bloodstream infections caused by E. coli and K. pneumoniae in patients with acute leukemia

Natalia A. Balshova¹, Ihar O. Stoma², Ihar A. Iskrou¹

PI-03. Influence of CMV serostatus of donor-recipient pairs on antiviral immunity reconstitution in the patients after allogeneic hematopoietic stem cell transplantation

Anna A. Dmitrova, Mikhail Yu. Drokov, Murad S. Vagida, Dmitriy O. Kiryukhin, Vera A. Vasilieva, Natalia N. Popova, Ekaterina D. Mikhaltsova, Mariya V. Dovydenko, Olga M. Koroleva, Daria S. Dubnyak, Zoya V. Konova, Mobil I. Akhmedov, Natalia M. Nikiforova, Uliyana V. Maslikova, Olga S. Starikova, Feruza A. Omarova, Elmira I. Kolgaeva, Dmitriy S. Tihomirov, Tatiana A. Tupoleva, Mikhail V. Demin, Larisa A. Kuzmina, Grigoriy A. Efimov, Elena N. Parovichnikova, Valery G. Savchenko

PI-04. Bloodstream infections in pediatric patients with CVCs after allogeneic HSCT: incidence, risk factors and outcome

Vladislav V. Kudlay, Olesya V. Paina, Polina V. Kozhokar, Yulia V. Bogoslavskaya, Irada M. Alieva, Galina N. Stolbenko

PI-05. Real-life large cohort single-center study on epidemiology of breakthrough invasive aspergillosis in the context of antifungal prophylaxis after allogeneic hematopoietic stem cell transplantation

Vladislav V. Markelov¹, Yulia A. Rogacheva¹, Marina O. Popova¹, Alisa G. Volkova¹, Ilya Yu. Nikolaev¹, Olga N. Pinegina¹, Nikita P. Volkov¹, Svetlana M. Ignatieva², Tatyana S. Bogomolova², Sergey N. Bondarenko¹, Nikolay N. Klimko^1,2, Alexander D. Kulagin¹

PI-06. Successful use of hydroxymethylquinoxalindexide in complex antimicrobial therapy treating patients with Gram-negative fulminant infectious complications during induced hematopoesis aplasia

Anastasia V. Mezentseva, Lyudmila V. Olkhova, Elena B. Machneva, Veronika V. Konstantinova, Alexandra E. Burya, Yulia A. Nikolaeva, Olga A. Filina, Basarma B. Purbueva, Olesya S. Fink, Michail M. Antoshin, Alya V. Martinenkova, Ekaterina A. Pristanskova, Elena V. Skorobogatova

Pediatric oncology: PO-01 – PO-05

PO-01. Neurological complications in children after hematopoietic stem cell transplantation: Single-center experience

Natalia V. Bronina, Evgeniy A. Burtsev, Inna O. Schederkina, Gleb O. Bronin

PO-02. High-dose chemotherapy and autologous hemopoietic stem cell transplantation effectiveness in patients with relapsed medulloblastoma: RM Gorbacheva Research Institute experience

Asmik G. Gevorgian, Ilya V. Kazantsev, Denis V. Kozlov, Polina S. Tolkunova, Tatiana V. Iukhta, Andrew V. Kozlov, Margarita S. Golenkova, Alexander N. Galimov, Olga I. Bogdanova, Alexander D. Kulagin, Yuri A. Punanov, Olga G. Zheludkova, Ludmila S. Zubarovskaya

PO-03. First pediatric cases of autologous hematopoietic stem-cell transplantation in Armenia

Mane S. Gizhlaryan^1,3, Karen H. Meliksetyan², Inga V. Khalatyan^1,2, Armine Pepanyan⁴, Andranik G. Shamilyan⁴, Medea G. Anastasiadi^1,2, Taguhi J. Hovhannisyan^1,2, Gevorg N. Tamamyan^1,3, Samvel H. Danielyan⁴, Lusine M. Krmoyan^1,2

PO-04. Dinutuximab beta immunotherapy after autologous and allogeneic hemopoietic stem cell transplantation in patients with high- and ultrahigh-risk group neuroblastoma: RM Gorbacheva Research Institute experience

Ilya V. Kazantsev, Asmik G. Gevorgian, Polina S. Tolkunova, Tatiana V. Iukhta, Daria A. Drozdovskaya, Andrew V. Kozlov, Margarita S. Golenkova, Alexander N. Galimov, Olga I. Bogdanova, Ekaterina V. Goncharova, Yuri A. Punanov, Alexander D. Kulagin, Ludmila S. Zubarovskaya

PO-05. Everolimus with tacrolimus for graft-versus-host disease prophylaxis in children with acute leukemia and JMML after allo-HSCT

Olesya V. Paina, Liubov A. Tsvetkova, Polina V. Kozhokar, Аnastasia S. Frolova, Zhemal Z. Rakhmanova, Elena V. Semenova, Alexander D. Kulagin, Ludmila S. Zubarovskaya

Posttransplant care and rehabilitation: PC-01 – PC-05

PC-01. Patient birthday celebration at the bone marrow transplant clinic during the COVID-19 pandemic

Rashida A. Bikulova, Anastasia A. Popova, Evgeniya S. Misyavichute, Svetlana I. Oleshko, Tatiana V. Kozlova, Angelica V. Pavlik, Alisa G. Volkova, Yulia A. Tarakanova, Galina N. Stolbenko

PC-02. Toxic skin lesions after chemotherapy and HSCT

Elvira A. Gasanova, Varvara N. Ovechkina, Nina N. Gurgenidze, Inga E. Zavodova, Anna A. Dotsenko, Tatyana A. Bykova

PC-03. Role of medical nurse in observation and evaluation of the patients after CAR-T therapy

Natalya P. Gusleva, Olga O. Molostova, Olga V. Pimenova, Larisa N. Shelikhova, Michael A. Maschan

PC-04. Complications of central venous catheters in patients undergoing hematopoietic stem cell transplantation in Armenia

Taguhi J. Hovhannisyan^1,2, Mane S. Gizhlaryan^1,3, Armine H. Farmazyan², Mira V. Saaryan², Yervand K. Hakobyan², Inga V. Khalatyan^1,2, Lusine M. Krmoyan^1,2, Mariam N. Fahradyan^1,2, Vahe A. Mailyan⁴, Davit N. Dallaqyan⁴, Medea G. Anastasiadi^1,2, Gevorg N. Tamamyan^1,3, Samvel H. Danielyan⁴, Karen H. Meliksetyan²

PC-05. Alcohol-associated avascular bone necrosis. Case report

Vsevolod G. Potapenko¹, Evgenij P. Burlachenko⁴, Alexej I. Berdes⁵, Inna M. Corablina³, Alexander I. Kazancev², Sergey L. Vorobyev³

Gene and cellular therapy: GC-01 – GC-15

GC-01. Development of methods for modifying nano- and microcarriers for in vitro and in vivo imaging

Darya R. Akhmetova¹, Timofey E. Karpov¹, Alisa S. Postovalova¹, Albert R. Muslimov², Alexander S. Timin¹, Mikhail V. Zyuzin³

GC-02. Ofatumumab-based CD20-specific CARs: in vitro and in vivo activity

Tatyana N. Belovezhets, Andrey A. Gorchakov, Sergey V. Kulemzin

GC-03. Increasing transfection level during delivery of genetic material by polymer carriers of complex composition

Anastasia S. Bukreeva¹, Anna S. Rogova¹, Tatiana V. Machel³, Darya R. Akhmetova¹, Alexander S. Timin^1,2, Albert R. Muslimov^1,2

GC-04. Development of the in vivo model of therapy for prostate cancer and assessment of antitumor activity of oncolytic viruses combined with CAR T-cell immunotherapy

Anton N. Chikaev¹, Sergey V. Kulemzin¹, Olga Yu. Volkova¹, Tatyana N. Belovezhets¹, Anastasiya V. Semenova², Sergey S. Zainutdinov², Antonina A. Grazhdantseva², Galina V. Kochneva²

GC-05. Long non-coding RNAs as potential targets for genome editing and gene therapy

Anton S. Dome, Dmitry V. Semenov, Grigory A. Stepanov

GC-06. Modification of silicon oxide nanocarriers with metal shells for capturing 225AC and its daughter isotopes

Тimofey Е. Karpov, Mikhail V. Zyuzin, Аlexander S. Timin, Dmitry О. Antuganov, Аlbert R. Muslimov

GC-07. Treatment of oncological diseases with micro-carriers using combined therapy

Alisa S. Postovalova¹, Timofey E. Karpov¹, Darya R. Akhmetova¹, Albert R. Muslimov², Alexander S. Timin¹, Mikhail V. Zyuzin³

GC-08. Study of the biodistribution of polymer carriers for further use in gene therapy

Anna S. Rogova¹, Anastasia S. Bukreeva¹, Alisa S. Postovalova¹, Darya R. Akhmetova¹, Alexander S. Timin^1,2, Albert R. Muslimov^1,2

GC-09. Testing of small molecules for homology-directed repair stimulation at CCR5 locus during the transfection of primary human hematopoietic stem cells by CCR5-Uco-TALEN mRNA

Alyona I. Shakirova¹, Kirill V. Lepik¹, Albert A. Muslimov¹, Vladislav S. Sergeev¹, T. R. Karpov¹, K. I. Anoshkin², Marina O. Popova¹, Boris Fehse^1,3, Alexander D. Kulagin¹

GC-10. Bioinformatic analysis of the RAD54L oncogene for detecting the effect on the occurrence of hematopoietic stem disorders

Bogdan O. Shcheglov

GC-11. Complications after chimeric antigen receptor T-cell therapy in adults

Antonina E. Shchekina, Gennady M. Galstyan, Olga A. Gavrilina, Zalina T. Fidarova, Vera V. Troitskaya, Vera A. Vasilyeva, Elena N. Parovichnikova, Michael A. Maschan

GC-12. Combining bispecifics and CARs: novel design of chimeric antigen receptor with CD3E extracellular domain for redirecting antitumor specificity with bispecific antibodies

Daniil I. Shmidt¹, Ivan N. Gaponenko¹, Nikita D. Yolshin², Olga S. Epifanovskaya¹, Tatyana N. Belovezhets³, Andrey A. Gorchakov³, Sergey V. Kulemzin³, Andrey M. Chekalov¹, Elena V. Babenko¹, Albert R. Muslimov¹, Vladislav S. Sergeev¹, Kirill V. Lepik¹, Alexander D. Kulagin¹

GC-13. Comparative assessment of cryopreservation conditions for K562 and mesenchymal stromal cells cultures

Irina A. Sidorova, Kirill V. Lepik, Albert R. Muslimov, M. A.Trofimov, Olga S. Epifanovskaya, Vladislav S. Sergeev, Alexander D. Kulagin

GC-14. CaCO3 dextran sulfate-coated vaterites as a system for regional doxorubicin administration

Natalia N. Sudareva^1,2, Olga M. Suvorova¹, Dmitry N. Suslov³, Oleg V. Galibin², Alexander D. Vilesov^1,2

GC-15. Investigation of the characteristics of micro-sized carriers, using “soft lithography” for packaging of genetic material

Anastasia A. Yakubova^1,2, Pavel M. Talianov³, Mikhail V. Zyuzin³, Albert R. Muslimov^1,2, Alexander S. Timin¹

Organizational issues and donorship: OD-01 – OD-08

OD-01. Increasing the HLA phenotypes diversity of potential hematopoietic stem cells donors

Alena V. Hlaz, Anatoly L. Uss

OD-02. Medication commitment of the patients before allo-HSCT

Elmira I. Kolgaeva, Mikhail Yu. Drokov, Dmitri E. Vybornykh, Natalia N. Popova, Zoya V. Konova, Natalia M. Nikiforova, Feruza A. Omarova, Olga S. Starikova, Ekaterina D. Mikhaltsova, Mariya V. Dovydenko, Olga M. Koroleva, Anna A. Dmitrova, Darya S. Dubnyak, Vera A. Vasilyeva, Larisa A. Kuzmina, Elena N. Parovichnikova, Valery G. Savchenko

OD-03. Red blood cell transfusion dosing for chronic anemia in children of different ages receiving anticancer therapy

Polina S. Kuga, Evgeny A. Bakin, Maxim A. Kucher, Boris A. Baryshev, Ludmila S. Zubarovskaya, Alexander D. Kulagin

OD-04. Benefits of centralized preparation of cytostatic drugs

Yulia V. Mirenkova

OD-05. Approaches, problems and prospects of nursing education in Russia

Natalia G. Petrova

OD-06. Optimization of blood transfusiology service at the First St. Petersburg State Medical University and improvement of hemocomponent supply for the patients subjected to transplantation of hematopoietic stem cells and solid organs

Dmitry E. Pevtsov, Bakhovadin B. Bakhovadinov, Boris A. Baryshev, Irina I. Kulagina, Maria A. Estrina, Maxim A. Kucher, Alexander D. Kulagin, Marina I. Likhacheva, Polina S. Kuga, Maria A. Sharapova

OD-07. Influence of the qualitative characteristics of thrombocyte concentrate on its clinical efficacy in the treatment of oncohematological patients

Maria A. Sharapova

OD-08. Prevalence of allele-specific anti-HLA-antibodies

Olga S. Starikova, Ekaterina G. Khamaganova, Mikhail Yu. Drokov, Igor Yu. Urybin, Vera A. Vasilieva, Ekaterina D. Mikhaltsova, Natalia N. Popova, Daria S. Dubnyak, Anna A. Dmitrova, Olga M. Koroleva, Natalia M. Nikiforova, Zoya V. Konova, Mobile I. Akhmedov, Maria V. Dovydenko, Ulyana V. Maslikova, Feruza A. Omarova, Elmira I. Kolgaeva, Anna S. Garmash, Larisa A. Kuzmina, Elena N. Parovichnikova, Valery G. Savchenko