Cellular Therapy and Transplantation

Cellular Therapy and Transplantation is an international, peer-reviewed, Open Access journal which publishes articles in the fields of cellular and gene therapy and tissue transplantation. We welcome original research articles, review articles, short communications and clinical case reports. The major criteria for acceptance and publication of a manuscript are originality, high quality, scientific rigor, and interest to a wide audience of readers. The journal is issued in printed and digital version (www.cttjournal.com)

Editorial work, processing and publication of the articles are free of charge for the authors.

Papers accepted for publication in CTT are made available on this site at no charge to readers (Open Access). The articles published in CTT are provided under the following license: Creative Commons Attribution 3.0 Unported, http://creativecommons.org/licenses/by/3.0/ Authors retain the copyright of their contributions.

Volume 12, Number 3 (Supplement)
09/30/2023

Editor-in-Chief
Kulagin A. D. (St. Petersburg, Russia)

Co-Editors-in-Chief
Wagemaker G. (Rotterdam, Netherlands)
Zander A. R. (Hamburg, Germany)

Deputy Editor
Fehse B. (Hamburg, Germany)

Managing Editor
Chukhlovin A. B. (St. Petersburg, Russia)

Editorial Board
Aleynikova O. V. (Minsk, Belarus)
Borset M. (Trondheim, Norway)
Chechetkin A. V. (St. Petersburg, Russia)
Fibbe W. (Leiden, Netherlands)
Gale R. P. (Los Angeles, USA)
Galibin O. V. (St. Petersburg, Russia)
Hehlmann R. (Mannheim, Germany)
Hölzer D. (Frankfurt a.M., Germany)
Kolb H.-J. (München, Germany)
Kröger N. (Hamburg, Germany)
Lange C. (Hamburg, Germany)
Mamaev N. N. (St. Petersburg, Russia)
Mikhailova N. B. (St. Petersburg, Russia)
Moiseev I. S. (St. Petersburg, Russia)
Nagler A. (Tel-Aviv, Israel)
Nemkov A. S. (St. Petersburg, Russia)
Paramonov I. V. (Kirov, Russia)
Roumiantsev A. G. (Moscow, Russia)
Smirnov A. V. (St. Petersburg, Russia)
Uss A. L. (Minsk, Belarus)
Zubarovskaya L. S. (St. Petersburg, Russia)

In this Issue

Editorial article

XVII Raisa Gorbacheva Memorial Meeting Hematopoietic Stem Cell Transplantation. Gene and Cellular Therapy

Alexander D. Kulagin, Editor-in-Chief, Cellular Therapy and Transplantation

Award Session: AW-01 – AW-05

AW-01. Simultaneous T-lymphocyte activation and B-lymphocyte elimination by bispecific monoclonal antibodies in the CAR-T production process

Ivan N. Gaponenko, Artem A. Potanin, Vladislav V. Markelov, Dina A. Senichchina, Vladislav S. Sergeev, Alena I. Shakirova, Kirill V. Lepik, Alexander D. Kulagin

AW-02. Development of a method for production of a third-generation lentiviral vector for the manufacturing of an anti-CD19 CAR-T cell product

Nataliya О. Ivanova, Yana V. Serdyuk, Еkaterina I. Fefelova, Dmitriy V. Dianov, Tatyana A. Nenasheva, Аpollinariya V. Bogolyubova

AW-03. Graft failure after allogeneic stem cell transplantation in patients with hereditary storage diseases

Olga A. Slesarchuk, Ekaterina N. Dolgushina, Polina V. Sheveleva, Anna A. Zvyagintseva, Anastasiya S. Borovkova, Anna A. Osipova, Natalia E. Ivanova, Ildar M. Barkhatov, Mariya O. Goloshchapova, Tatiana A. Bykova, Alexander D. Kulagin, Ludmila S. Zubarovskaya

AW-04. Experience of patient follow-up after withdrawal of opioid analgesics

Konstantin V. Shchedrin, Ekaterina V. Goncharova, Maxim A. Kucher

AW-05. On the importance of communication skills in working with critically ill patients

Tatyana M. Semchishina

Acute leukemias: AL-01 – AL-10

AL-01. The role of allogeneic hematopoietic stem cell transplantation in adult patients with Ph-negative lymphoblastic leukemia due to the high risk of recurrence in a prospective multicentre randomized study RALL-2016

Olga A. Aleshina¹, Ekaterina S. Kotova¹, Irina V. Galtseva¹, Tatiana N. Obukhova¹, Valentina N. Dvirnyk¹, Andrey B. Sudarikov¹, Galina A. Isinova¹, Anastasia N. Vasilyeva¹, Maria E. Grishunina², Olga S. Samoilova², Kamil D. Kaplanov³, Valeriy A. Lapin⁴, Sergey N. Bondarenko⁵, Natalia V. Minaeva⁶, Yulia V. Sveshnikova⁷, Elena E. Zinina⁸, Alina S. Antipova⁹, Olga Yu. Baranova⁹, Elena A. Borisenkova¹⁰, Yulia A. Chabaeva¹, Sergey M. Kulikov¹, Elena N. Parovichnikova¹

AL-02. Dynamics of the mRNA WT1, PRAME, EVI1, BAALC, and HMGA2 genes during therapy of acute promyelocytic leukemia

Alexey S. Gorbenko, Marina A. Stolyar, Varvara I. Bakhtina, Vladislav V. Galanin, Igor A. Olkhovskiy

AL-03. Donor chimerism in the peripheral blood at the day +14 after allo-HSCT predicts graft failure

Olga E. Dubova^1,2, Mikhail Yu. Drokov¹, Natalia V. Risinskaya¹, Yulia A. Chabaeva¹, Firuza K. Shikhveledova¹, Anna A. Yushkova¹, Uliana V. Maslikova¹, Inara S. Saidullaeva¹, Dmitriy S. Tikhomirov¹, Sergei M. Kulikov¹, Larisa A. Kuzmina¹, Andrey B. Sudarikov¹

AL-04. Risk-adapted immunoglobulin replacement therapy in patients with acute leukemia: clinical evaluation and comparative analysis

Olga V. Gerasimovich¹, Igor A. Iskrov², Irina Yu. Lendina¹

AL-05. The efficiency of combination azacitidine and venetoclax therapy in elderly patients at the first-line therapy, and in refractory/relapsed cases of acute myeloid leukemia

Maxim A. Granatkin^1,2, Maria I. Kislova¹, Evgeny S. Mikhailov¹, Maria M. Okuneva^1,2, Anna V. Antonova¹, Natalya V. Degtyareva¹, Yury N. Kobzev¹, Vadim A. Doronin¹, Evgeny A. Nikitin^1,2

AL-06. The outcomes of hematopoietic stem cell transplantation in pediatric patients with chemorefractory acute myeloid leukemia

Maria A. Ilyushina, Larisa N. Shelikhova, Daria A. Shasheleva, Elena E. Kurnikova, Yakov O. Muzalevsky, Irina I. Kalinina, Galina A. Novichkova, Aleksey A. Maschan, Michael A. Maschan

AL-07. Pre-transplant minimal residual disease as an unfavorable prognostic factor in patients with acute myeloid leukemia in the first complete remission

Zoya V. Konova, Irina V. Galtseva, Yulia O. Davydova, Nikolay M. Kapranov, Maria V. Dovydenko, Ekaterina D. Mikhaltsova, Natalia N. Popova, Feruza A. Omarova, Elmira I. Kolgaeva, Daria A. Mironova, Luiza A. Karaseva, Olga M. Koroleva, Daria S. Dubnyak, Olga S. Karavaeva, Uliana V. Maslikova, Vera V. Vasilyeva, Larisa A. Kuzmina, Elena N. Parovichnikova

AL-08. Extramedullary acute myeloid leukemia: could the new targets and allogeneic stem cell transplantation improve outcomes?

Aleksina A. Shatilova, Irina G. Budaeva, Yuliya D. Matvienko, Yuliya V. Mirolyubova, Darya V. Ryzhkova, Roman V. Grozov, Konstantin V. Bogdanov, Tatiana S. Nikulina, Ksenia A. Levchuk, Renat S. Badaev, Yuliya A. Alekseeva, Elza G. Lomaia, Larisa L. Girshova

AL-09. Significance of immunophenotypic markers in adult patients with T-cell lymphoblastic leukemia

Anastasia N. Vasilyeva, Olga A. Aleshina, Tatiana N. Obukhova, Valentina N. Dvirnyk, Ekaterina I. Zakharko, Elena N. Parovichnikova

AL-10. Outcomes of haploidentical, matched and mismatched unrelated transplantations with posttransplant cyclophosphamide in first complete remission of acute myeloid leukemia

Dmitrii K. Zhogolev, Sergey N. Bondarenko, Anna G. Smirnova, Yulia Yu. Vlasova, Bella I. Ayubova, Nikita P. Volkov, Tatyana A. Rudakova, Daria A. Chernyshova, Alexander L. Alyanskiy, Natalia E. Ivanova, Elena V. Babenko, Ildar M. Barkhatov, Tatiana L. Gindina, Elena V. Morozova, Ivan S. Moiseev, Alexander D. Kulagin

Lymphoproliferative disorders: LP-01 – LP-11

LP-01. Pre-transplant therapy in a pediatric patient with relapsed primary mediastinal large B cell lymphoma: a case report

Alexander N. Galimov, Andrey V. Kozlov, Ilya V. Kazantsev, Tatiana V. Grishchenko, Vadim V. Baykov, Alexander N. Shvetsov, Ilya Y. Nikolaev, Margarita S. Khalipskaya, Polina S. Tolkunova, Olga I. Bogdanova, Natalia B. Mikhailova, Yuri A. Punanov, Alexander D. Kulagin, Ludmila S. Zubarovskaya

LP-02. Efficacy of allogeneic hematopoietic cell transplantation in cutaneous T-cell lymphomas

Liliya G. Gorenkova, Larisa A. Kuzmina, Yana K. Mangasarova, Evgenii E. Zvonkov, Elena N. Parovichnikova

LP-03. Pain syndrome and mental disorders caused by mucositis at an early stage after auto-HSCT in patients with multiple myeloma

Elmira Z. Irugova, Dmitry E. Vybornykh, Maksim V. Solovev, Larisa P. Mendeleeva

LP-04. Allogeneic hematopoietic stem cell transplantation for mature T/NK-cell lymphomas in children

Maria A. Klimentova, Margarita E. Perminova, Larisa N. Shelikhova, Sergey L. Blagov, Olga O. Molostova, Yulia G. Abugova, Natalia V. Myakova, Michael A. Maschan

LP-05. Stem cell mobilization and collection in HIV-positive patients with lymphoma: candidates to autologous HSCT

Yaroslava V. Komarova, Marina O. Popova, Andrey M. Chekalov, Ivan V. Tsygankov, Liliya V. Stelmakh, Lyudmila V. Fedorova, Kirill V. Lepik, Natalia B. Mikhailova, Maria A. Estrina, Elena V. Babenko, Maria D. Vladovskaya, Sergey N. Bondarenko, Ivan S. Moiseev, Alexander D. Kulagin

LP-06. Conditioning regimen dose reduction in patients with lymphomas undergoing autologous hematopoietic stem cell transplantation: a retrospective-prospective matched cohort study

Polina V. Kotselyabina, Vladislav V. Kovalik, Artem S. Ivanov, Kirill V. Lepik, Andrey M. Chekalov, Liudmila V. Fedorova, Elena E. Lepik, Olesia G. Smykova, Vladislav V. Markelov, Evgenia S. Borzenkova, Elena V. Kondakova, Ivan S. Moiseev, Natalia B. Mikhailova, Alexander D. Kulagin

LP-07. Efficiency of autologous hematopoietic stem cell transplantation in patients with multiple myeloma complicated by bone plasmacytomas

Elizaveta A. Mamaeva, Maiia V. Soloveva, Maxim V. Solovev, Irina E. Kostina, Larisa P. Mendeleeva

LP-08. Experience with CAR-T-cell therapy in the treatment of indolent and aggressive lymphomas

Ekaterina S. Nesterova, Aminat U. Magomedova, Lilia G. Gorenkova, Oleg V. Margolin, Runisa R. Abdurashidova, Ekaterina A. Fastova, Madina O. Bagova, Sergey K. Kravchenko, Evgeny E. Zvonkov, Yana K. Mangasarova

LP-09. Clinical case of multiple myeloma treated with IsaPD triplet after autologous HSCT

Оksana Е. Ochirova, Erzhena B. Zhalsanova, Alina G. Karpova, Anna N. Alexeeva, Elena Zh. Bykova, Irina S. Ulanova, Ailana V. Sodboeva, Tumen V. Dondokov

LP-10. Paraprotein associated polyneuropathy: A case series

Vsevolod G. Potapenko¹, Yana B. Kushnir², Vasily N. Kiselev⁴, Julia V. Zabutova¹, Sergey M. Zatakovenko³, Natalia A. Totolyan², Natalia A. Kotova¹, Olga V. Kudyasheva², Dmitry I. Rudenko^2,3, Irina A. Samorodova¹, Alexander V. Serkov¹, Olga V. Nebelitskaya¹, Nadezhda V. Medvedeva¹

LP-11. Decreased concentration of circulating BCMA protein after autologous transplantation of hematopoietic stem cells in multiple myeloma patients

Anton A. Startsev, Maksim V. Solovev, Valentina N. Dvirnyk, Maria N. Panasenko, Maya V. Soloveva, Alexandra V. Abakumova, Elizaveta A. Mamaeva, Victoria A. Khyshova, Larisa P. Mendeleeva

Chronic myeloproliferation: MP-01 – MP-09

MP-01. Features of therapeutic strategy in patients with CMML

Svetlana E. Durova, Nikita P. Volkov, Elena V. Morozova, Yulia Yu. Vlasova, Ivan S. Moiseev, Alexander D. Kulagin

MP-02. Allogeneic hematopoietic stem cell transplantation in patients with secondary myelodysplastic syndrome or leukemia evolving from aplastic anemia and paroxysmal nocturnal hemoglobinuria

Irina K. Golubovskaya, Maria V. Marchenko, Nikolay Y. Tsvetkov, Anna A. Osipova, Elena V. Morozova, Alexander D. Kulagin

MP-03. Successful treatment of testicular myeloid sarcoma with azacitidine and venetoclax: Case report

Anastasiia I. Kashlakova, Irina A. Lukianova, Zalina T. Fidarova, Alla M. Kovrigina, Valentina N. Dvirnyk, Tatyana N. Obukhova, Andrey B. Sudarikov, Vera V. Troitskaya, Elena N. Parovichnikova

MP-04. A clinical case of the donor-derived myelodysplastic syndrome after allogeneic bone marrow transplantation

Olga M. Koroleva, Alina V. Kochno, Luiza A. Karaseva, Natalya A. Petinati, Vera A. Vasilyeva, Marya V. Dovydenko, Zoya V. Konova, Dmitry A. Mokin, Tatyana N. Obukhova, Larisa A. Kuzmina, Elena N. Parovichnikova

MP-05. Results of allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis

Olga S. Pokrovskaya, Larisa A. Kuzmina, Zoya V. Konova, Vera A. Vasilyeva, Maria V. Dovydenko, Olga M. Koroleva, Anait L. Melikyan, Karen I. Danishyan, Elena N. Parovichnikova

MP-06. Functional evaluation of telomeric complex genes in patients with myelodysplastic syndrome and acute myeloid leukemia

Ayrat M. Sadykov, Dmitriy S. Bug, Nikolay Yu. Tsvetkov, Ildar M. Barkhatov

MP-07. Effectiveness of post-transplant cyclophosphamide in children and adolescents with chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning regimens

Polina V. Sheveleva, Elena V. Morozova, Anna A. Osipova, Olesya V. Paina, Olga A. Slesarchuk, Kirill A. Ekushov, Tatyana L. Gindina, Nikolay N. Mamaev, Ekaterina A. Izmailova, Ildar M. Barkhatov, Tatyana A. Bykova, Elena V. Semenova, Alexander D. Kulagin, Ludmila S. Zubarovskaya

MP-08. Evaluation of hemostatic balance in patients with Ph-negative myeloproliferative neoplasms

Natalia N. Silina, Olga G. Golovina, Natalia E. Korsakova, Olesya Yu. Matvienko, Elizaveta V. Efremova, Sergey V. Voloshin

MP-09. Characteristics and results of treatment of patients with blast crisis of chronic myeloid leukemia who did not receive allogeneic hematopoietic stem cell transplantation

Julia S. Yakovleva, Ksenia S. Tsvirko, Yulia Yu. Vlasova, Ivan S. Moiseev, Elena V. Morozova, Tatiana L. Gindina, Alexander D. Kulagin

Non-malignant disorders: NM-01 – NM-09

NM-01. Haploidentical stem cell transplantation for aplastic anemia patients: one-center experience

Zalina T. Fidarova, Dmitry K. Bessmertnyy, Anton V. Luchkin, Mikhail Y. Drokov, Anastasia V. Abramova, Artur V. Bulgakov, Vera V. Troitskaya, Larisa A. Kuzmina, Elena A. Mikhailova

NM-02. Long-term outcomes following hematopoietic stem cell transplantation in patients with Fanconi anemia: results from a single center

Anastasia V. Doronina, Elena B. Machneva, Ludmila V. Olkhova, Yulia A. Nikolaeva, Mariia S. Kuricina, Michail M. Antoshin, Ekaterina A. Pristanskova, Elena V. Skorobogatova

NM-03. Congenital giant nevi in children: problems of patients, methods and opportunities of treatment in Russia

Olga V. Filippova, Yaroslav N. Proshchenko, Dmitry I. Grigorov, Ekaterina N. Provorova

NM-04. The experience of hematopoietic stem cell transplantation for thalassemia major at the Morozov Children’s Hospital

Bulat M. Kurmanov, Irina O. Vlasova, Anna V. Lifshits, Georgiy Z. Seregin, Maria R. Zhuravel, Gleb O. Bronin, Ella V. Kumirova, Michael A. Maschan

NM-05. Histological characteristic of nasal mucosa after the usage of mesenchymal stem cells in the treatment of chronic polyposis rhinosinusitis: preliminary results of observation

Anastasia A. Nidelko¹, Elvira A. Shulepova², Svetlana N. Ryabtseva³, Veronika E. Mantivoda⁴, Natalia G. Antonovich⁴, Andrey E. Goncharov⁴, Valery L. Chekan², Yulia E. Eremenko¹

NM-06. Results of allogenic hematopoietic stem cell transplantation for bone marrow failure syndrome in non-malignant diseases in children: single center experience

Tatyana I. Potemkina¹, Irina O. Kostareva¹, Yuriy V. Lozovan¹, Nataliya A. Burlaka¹, Timur Z. Aliev¹, Karina A. Sergeenko¹, Elena B. Machneva^1,2, Kirill I. Kirgizov¹

NM-07. Treosulfan-based conditioning for hematopoietic stem cell transplantation in patients with Diamond-Blackfan anemia

Svetlana A. Radygina, Svetlana N. Kozlovskaya, Anna P. Vasilieva, Irina P. Shipitsina, Аnna А. Bogoyavlenskaya, Larisa N. Shelikhova, Yulia V. Skvortsova, Dmitry N. Balashov, Michael A. Maschan

NM-08. Transplantation from matched unrelated donors in pediatric severe aplastic anemia: TCR alpha/beta and CD19 depletion of the graft is associated with high survival and low GvHD rates

Daria A. Shasheleva, Larisa N. Shelikhova, Dmitriy N. Balashov, Olga O. Molostova, Svetlana N. Kozlovskaya, Maria A. Ilyushina, Elena E. Kurnikova, Yakov O. Muzalevsky, Alexei S. Kazachenok, Varvara V. Briliantova, Elena V. Raikina, Dina D. Baidildina, Rimma D. Khismatullina, Sergey L. Blagov, Elena V. Suntsova, Michael A. Maschan, Alexei A. Maschan, Galina A. Novichkova

NM-09. Allogeneic transplantation of hematopoietic stem cells in cases of congenital immunity disorders in the Republic of Belarus

Lyubov V. Zherko, Yulia E. Mareyko, Natalya P. Kirsanova, Olga A. Mishkova, Nina V. Minakovskaya

Posttransplant complications: PC-01 – PC-07

PC-01. Immune-mediated damage of nervous system after hematopoietic stem cell transplantation

Natalia V. Bronina, Bulat M. Kurmanov, Evgeny A. Burtsev, Georgy Z. Seregin, Maria V. Natrusova, Inna O. Shchederkina, Gleb O. Bronin, Ella V. Kumirova, Michael A. Maschan

PC-02. Usage of vedolizumab in the treatment of GvHD in children: experience of the N. N. Blokhin National Medical Research Center of Oncology

Natalia A. Burlaka, Karina A. Sergeenko, Irina O. Kostareva, Teymur Z. Aliev, Konstantin V. Mitrakov, Tatiana I. Potemkina, Vasily P. Akimov, Nune V. Matinyan, Dmitry V. Rogozhin, Timur T. Valiev, Natalia A. Batmanova, Elena B. Machneva, Kirill I. Kirgizov, Svetlana R. Varfolomeeva

PC-03. Transplantation of maternal oral microbiota to a child for the prevention of mucositis: a clinical case

Oleg V. Goloshchapov¹, Alexey B. Chukhlovin¹, Dmitrii S. Bug², Dmitriy E. Polev³, Oleg V. Kosarev⁴, Ruslana V. Klementeva¹, Ekaterina A. Izmailova¹, Ilya V. Kazantsev¹, Margarita S. Khalipskaia¹, Мaria О. Goloshchapova¹, Olesya S. Yudintseva¹, Ildar M. Barkhatov¹, Natalia V. Petukhova², Ludmila S. Zubarovskaya¹, Alexander D. Kulagin¹, Ivan S. Moiseev¹

PC-04. Risk factors for the development of graft dysfunction after allogeneic hematopoietic stem cell transplantation

Ulyana V. Maslikova¹, Ekaterina D. Mikhaltsova¹, Alexey A. Glazkov², Olga S. Karavaeva¹, Luiza A. Karaseva¹, Feruza A. Omarova¹, Elmira I. Kolgaeva¹, Inara S. Saidullayeva¹, Darya A. Mironova¹, Zoya V. Konova¹, Henrik Grigoryan², Vera A. Vasilieva¹, Larisa A. Kuzmina¹, Mikhail Y. Drokov¹, Ekaterina G. Khamaganova¹, Elena N. Parovichnikova¹

PC-05. Comparison of carbapenem-resistant gut colonization surveillance methods in early period of allogeneic hematopoietic stem cell transplantation

Ekaterina D. Markovina, Yuliya A. Rogacheva, Marina O. Popova, Aleksandr A. Siniaev, Oleg V. Goloshchapov, Yulia Yu. Vlasova, Sergey N. Bondarenko, Alexander D. Kulagin

PC-06. Zonulin and calprotectin as markers of posttransplantation complications after allogeneic hematopoietic stem cell transplantation

Anastasia I. Reshetova, Dmitry V. Motorin, Darina B. Zammoeva, Renat Sh. Badaev, Alexey S. Golovkin

PC-07. Achievement of organ-specific response depending on FEV1 values in patients with pulmonary chronic graft-versus-host disease

Vera A. Vasilyeva, Larisa A. Kuzmina, Mikhail Yu. Drokov, Mariya V. Dovydenko, Olga M. Koroleva, Olga S. Karavaeva, Darya S. Dubnyak, Ulyana V. Maslikova, Elena N. Parovichnikova

Pediatric oncology: PO-01 – PO-11

PO-01. Results of HSC transplantation in children with solid malignant neoplasms: Experience at the N. N. Blokhin National Medical Research Center of Oncology

Teymur Z. Aliev, Elena B. Machneva, Karina A. Sergeenko, Irina O. Kostareva, Nara G. Stepanyan, Yuri V. Lozovan, Tatiana I. Potemkina, Natalia A. Burlaka, Amina M. Suleimanova, Marina V. Rubanskaya, Garik B. Sagoyan, Olga M. Romantsova, Lana M. Kudaeva, Anatoly P. Kazantsev, Vladimir G. Polyakov, Kirill I. Kirgizov, Svetlana R. Varfolomeeva

PO-02. Haploidentical versus matched unrelated HSCT with post transplant cyclophosphamide based GvHD prophylaxis in children with acute leukemia

Anastasiia S. Borovkova, Olesia V. Paina, Zhemal Z. Rakhmanova, Polina V. Kozhokar, Anastasiia S. Kalinichenko, Liubov A. Tsvetkova, Svetlana V. Razumova, Kirill A. Ekushov, Anna A. Osipova, Olga A. Slesarchuk, Tatiana A. Bykova, Elena V. Semenova, Alexander D. Kulagin, Ivan S. Moiseev, Ludmila S. Zubarovskaya

PO-03. Targeted therapy for treatment of Langerhans cell histiocytosis reactivation in pediatric patients without “risk organ” involvement

Evgeniy A. Burtsev, Gleb O. Bronin

PO-04. Experience in high-dose chemotherapy with autologous hematopoietic stem cell transplantation in children in Chelyabinsk Region

Maria V. Danilova, Sergei G. Kovalenko, Svetlana E. Tsvetkova, Elena V. Kopytova, Karine B. Volkova, Maria V. Bogacheva, Irina I. Spichak

PO-05. Experience with CXCR4 antagonist (Plerixafor) in pediatric clinic at the R. Gorbacheva Memorial Instotute of Pediatric Oncology, Hematology and Transplantation

Margarita S. Khalipskaya, Polina S. Kuga, Ilya V. Kazantsev, Maria A. Estrina, Elena V. Babenko, Alexander N. Galimov, Daria A. Drozdovskaya, Olesya S. Yudintseva, Tatiana V. Grishchenko, Polina S. Tolkunova, Olga I. Bogdanova, Andrei V. Kozlov, Svetlana A. Safonova, Yuri A. Punanov, Ludmila S. Zubarovskaya

PO-06. Innovation approaches to total body irradiation with simultaneous dose escalation to bone marrow in children with oncohematological diseases

Daria A. Kobyzeva, Anna A. Loginova, Larisa N. Shelikhova, Francheska Ya. Kanestri, Rimma D. Khismatullina, Maria A. Ilyushina, Michael A. Maschan, Aleksey V. Nechesnuyk

PO-07. Post-transplant Cyclophosphamide (PTCy), abatacept and vedolizumab in GvHD prophylaxis in hematopoietic stem cells transplantation from matched unrelated and haploidentical donors in pediatric acute leukemia patients

Margarita E. Perminova, Larisa N. Shelikhova, Andrey B. Abrosimov, Maria A. Dunaykina, Maria A.Klimentova, Maria A. Ilyushina, Yakov O. Muzalevsky, Dmitriy N. Balashov, Alexey A. Maschan, Michael A. Maschan

PO-08. Transplantation of TCRαβ+/CD19+ depleted hematopoietic stem cells: prediction and management of depletion depth

Alexander I. Ponomarev^1,2,3, Grigory A. Tsaur^1,2,3, Tatyana Yu. Verzhbitskaya^1,2, Jean V. Permikin^1,3, Larisa V. Vakhonina^1,2, Anna A. Vlasova¹, Larisa G. Fechina^1,2

PO-09. Tandem autologous transplantation of hematopoietic stem cells in children with germ cell tumors: experience of N. N. Blokhin center

Karina A. Sergeenko, Natalia A. Burlaka, Tatiana I. Potemkina, Konstantin V. Mitrakov, Teimour Z. Aliev, Irina O. Kostareva, Nara G. Stepanyan, Elena B. Machneva, Olga A. Kapkova, Marina V. Rubanskaya, Anatoly P. Kazantsev, Vladimir G. Polyakov, Kirill I. Kirgizov, Svetlana R. Varfolomeeva

PO-10. Incidence and clinical characteristics of relapse with loss of HLA heterozygosity after haplo-HSCT in children with acute lymphoblastic leukemia

Liubov A. Tsvetkova, Aleksey A. Evdokimov, Ildar M. Barkhatov, Olesya V. Paina, Olga S. Epifanovskaya, Elena V. Babenko, Zhemal Z. Rakhmanova, Polina V. Kozhokar, Anna A. Osipova, Аnastasia S. Frolova, Elena V. Semenova, Alexander D. Kulagin, Ludmila S. Zubarovskaya

PO-11. Comparative analysis of ex vivo and in vivo TCRαβ+ depletion in hematopoietic stem cell transplantation

Anna A. Vlasova¹, Larisa V. Vakhonina^1,2, Natalya G. Maisheva^1,2, Dmitry E. Klevakin¹, Andrey A. Igumenshchev^1,2, Tatyana Yu. Verzhbitskaya^1,2, Alexander I. Ponomarev^1,2,3, Jean V. Permikin^1,3, Grigory A. Tsaur^1,2,3, Larisa G. Fechina^1,2

Rehabilitation: R-01 – R-05

R-01. Clinical and pharmacoeconomic aspects of rehabilitation in oncohematology and the significance of non-profit organizations (NPO) in the development of rehabilitation

Andrey B. Abrosimov^1,2, Yulia V. Devyatovskaya²

R-02. Features of the physical status of a child treated for cancer which determine the personified rehabilitation strategy

Serafima M. Chechelnitskaia, Aleksandra V. Baerbakh, Daria V. Zhuk

R-03. Relationships between reading and emotional/social well-being of children with oncological diseases

Nataliya M. Kurikalova

R-04. Physical factors in spa rehabilitation of the children with oncohematological disorders

Victoria Yu. Plisetskaya¹, Natalya Yu. Solomkina²

R-05. Establishment of pioneering spiritual rehabilitation center helping pediatric cancer survivors and their families

Anush Sargsyan, Saten Hovhannisyan, Alisa Qamalyan, Samvel Danielyan, Gevorg Tamamyan

Nursery: N-01 – N-05

N-01. Current Issues of Nursing in Oncology, Hematology and bone marrow transplantation: Initial results and prospects of supplementary professional training program at the St. Petersburg Pavlov University

Tamara V. Chikicheva¹, Yulia V. Devyatovskaya², Maria M. Ivannikova²

N-02. Comparison of low-bacterial and modified diet in HSCT adult patients

Tamara A. Gogoleva

N-03. The role of nurse in extracorporeal photopheresis

Yuliya V. Mirenkova

N-04. Features of care for the patients with tumors of central nervous system at the stage of HSCT

Lyubov A. Shepeleva, Ilya V. Kazantsev, Polina S. Tolkunova, Tatiana V. Grishchenko, Olga I. Bogdanova, Margarita S. Khalipskaya, Denis V. Kozlov

N-05. Chemotherapy: preparation and rehabilitation of the patient

Natalia A. Stolbova, Tatiana A. Tereshko, Svetlana V. Poponina

Donorship and typing: DT-01 – DT-10

DT-01. Graft preservation in haploidentical SCT with post-transplant cyclophosphamide: single center experience

Renat S. Badaev¹, Darina B. Zammoeva¹, Anastasiya I. Reshetova¹, Vasiliy S. Chistyakov¹, Alexander Yu. Pestakov¹, Larisa L. Girshova¹, Irina G. Budaeva¹, Nadiya T. Siordiya¹, Yuliya A. Alekseeva¹, Elza G. Lomaia¹, Dmitriy V. Motorin², Andrey Yu. Zaritskey¹

DT-02. Accompanying bone marrow and hematopoietic stem cell donors

Olga A. Gerova, Inna A. Chernysheva, Ekaterina I. Davlyatkhanova

DT-03. Determination of weak D antigen in blood donors using molecular genetic typing

Svetlana V. Gavrovskaya, Natalia V. Mineeva, Elena A. Sysoeva

DT-04. Antibodies to human leukocyte antigens (HLA) in patients with multiple myeloma

Elena V. Kuzmich, Irina E. Pavlova, Ivan I. Kostroma, Sergey V. Gritsaev

DT-05. Influence of placenta-derived mesenchymal stromal cell on clonogenic potential of deposited cord blood hematopoietic stem cells

Maria A. Novikova, Yanina I. Isaikina, Yuliya V. Savich, Elena G. Liakh

DT-06. Experience with potential hematopoietic stem cells donors at the Russian Research Institute of Hematology and Transfusiology

Irina E. Pavlova, Elena V. Kuzmich, Sergey V. Sidorkevich, Lyudmila N. Bubnova

DT-07. Working experience of Search Department at the National V. Perevoshchikov Bone Marrow Donor Registry with international marrow donor registries

Galina A. Pisugina, Ekaterina I. Davlyathanova, Ilyas R. Fatyykhov, Olga A. Gerova

DT-08. Experience in arranging the Irkutsk segment of the Federal Register of Bone Marrow Donors

Natalia O. Saraeva¹, Maxim V. Zarubin²

DT-09. Prevalence of human herpes viruses 6A and 6B among bone marrow donors

Inara S. Saidullayeva, Mikhail Y. Drokov, Tatyana A. Tupoleva, Dmitriy S. Tikhomirov, Tatiana A. Soldatova, Mikhail A. Demin, Elvira A. Domonova, Maria V. Dovydenko, Ekaterina D. Mikhaltsova, Natalia N. Popova, Zoya V. Konova, Feruza A. Omarova, Elmira I. Kolgaeva, Daria A. Mironova, Luiza A. Karaseva, Olga M. Koroleva, Daria S. Dubnyak, Olga S. Karavaeva, Ulyana V. Maslikova, Vera A. Vasilieva, Larisa A. Kuzmina, Olga S. Pokrovskaya, Elena N. Parovichnikova

DT-10. Analysis of the collection center activities at the National Medical Research Center for Hematology

Vera A. Vasilyeva, Olga S. Karavaeva, Feruza A. Omarova, Uliana V. Maslikova, Elmira I. Kolgaeva, Tatyana V. Gaponova, Larisa A. Kuzmina, Elena N. Parovichnikova

Basic Studies: BS-01 – BS-09

BS-01. Prospects for the use of polymer and polymer-modified structure particles in approaches to gene therapy of diseases of the gastrointestinal tract

Darya R. Akhmetova, Anna S. Rogova, Alice S. Postovalova, Alexandra V. Brodskaya

BS-02. Characteristics of PD-1- and TIM-3-expressing T cells in multiple myeloma patients

Egor V. Batorov, Tatyana A. Aristova, Vera V. Denisova, Svetlana A. Sizikova, Galina Yu. Ushakova, Alexandr A. Ostanin, Elena R. Chernykh

BS-03. In vitro study of functional and immunophenotypic features of anti-CD19 CAR T cell therapy derived from T lymphocytes of healthy donors and patients with B cell malignancies

Ekaterina I. Fefelova, Yana V. Serdyuk, R. Salman, Tatyana A. Nenasheva, Nataliya O. Ivanova, Apollinariya V. Bogolyubova

BS-04. Development of a new bioimaging system based on barium carbonate particles for the diagnosis of malignant neoplasms

Timofey E. Karpov^1,2, Aya Darwish¹, Alexander S. Timin^1,2, Sergey A. Shipilovskikh^1,2, Alisa S. Postovalova^1,2, Mikhail V. Zyuzin²

BS-05. Efficacy of genetic modification of CCR5 locus by specific CCR5-Uco-hetTALEN nuclease in hematopoietic stem cell subfraction with potential for long-term recovery of stable hematopoiesis

Valeriia O. Laushkina, Vladislav S. Sergeev, Olga S. Epifanovskaya, Marina O. Popova, Alena I. Shakirova, Kirill V. Lepik, Alexander D. Kulagin

BS-06. Studying efficiency of T-cell transduction in microfluidic systems for creation of T-lymphocytes with chimeric antigen receptor

Vladislav V. Markelov¹, Konstantin V. Arabuli², Ivan N. Gaponenko¹, Vladislav S. Sergeev¹, Dina A. Senichkina¹, Artem A. Potanin¹, Valeriia O. Laushkina¹, Mikhail V. Zyuzin², Alena I. Shakirova¹, Kirill V. Lepik¹, Alexander D. Kulagin¹

BS-07. Development of magnetic nanoscale systems suitable for clinical selection of therapeutically relevant populations of human cells

Timofey A. Pyatiizbyantsev¹, Aya Darwish², Olga S. Epifanovskaya¹, Alexander S. Timin², Ksenia A. Mitusova², Alena I. Shakirova¹, Kirill V. Lepik¹

BS-08. Development of a PD-L1 and Tim-3 expression model using human myeloid cell lines for investigating the activity of small molecule inhibitors of immune checkpoints signaling pathways

Dina A. Senichkina¹, Alena I. Shakirova¹, Olga S. Epifanovskaya¹, Ivan N. Gaponenko¹, Yekaterina V. Belotserkovskaya², Anna B. Malyshecheva², Kirill V. Lepik¹, Ivan S. Moiseev¹

BS-09. Generation of CAR-T cell product for the treatment of resistant CD19-positive B-cell lymphomas

Ihar M. Seviaryn¹, Hanna A. Saurytskaya¹, Nadezhda M. Bobrova¹, Aliaksei A. Beliayeuski¹, Tatiana M. Doroshenko¹, Volha A. Kalenik¹, Alexander A. Migas¹, Anna S. Portyanko¹, Natalia Y. Konoplya¹